CRO服务

Herpes Simplex Virus (HSV)

单纯疱疹病毒(HSV)

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服务内容

产品信息

病毒编号

病毒名称

病毒颜色及用途

H01001

HSV-EGFP

绿色,顺向跨多级

H01002

HSV-tdTomato

红色,顺向跨多级

H02003

HSV-LSL-tdtomato-2a-TK(H356)

红色,cre依赖,顺向跨多级

H03001

HSV-ΔTK-hUbC-tdTomato

红色,不跨突触,与AAV-TK连用可实现顺向跨单级

H03002

HSV-ΔTK-LSL-tdTomato(H361)

红色,不跨突触,cre依赖,与AAV-TK连用可实现顺向跨单级

参考文献

1. Bowers W J, Mastrangelo M A, Stanley H A, et al. HSV amplicon-mediated Abeta vaccination in Tg2576 mice:differential antigen-specific immune responses[J].Neurobiol Aging, 2005,26(4):393-407.

2. Frazer M E, Hyghes J E, Mas trangelo M A, et al. Reduced pathology and improved behavioral performance in Alzheimer’s disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4[J]. Mol Ther, 2008, 16(5):845-853.

3. Coen, D.M., Kosz-Vnenchak, M., Jacobson, J.G., Leib, D.A., Bogard, C.L., Schaffer, P.A., Tyler, K.L., and Knipe, D.M. (1989). Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.Proceedings of the National Academy of Sciences of the United States of America 86, 4736-4740.

4. Li, X., Chen, W., Pan, K., Li, H., Pang, P., Guo, Y., Shu, S., Cai, Y., Pei, L., Liu, D., et al. (2018). Serotonin receptor 2c-expressing cells in the ventral CA1 control attention via innervation of the Edinger-Westphal nucleus. Nature neuroscience 21, 1239-1250.

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BD:17720514121(BD总监)/ 13886000399(BD经理)/ 17720511475(BD经理)

本公司所有产品仅供实验科研使用,不用于人体疾病治疗及临床诊断。

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